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The following information contains results of independent laboratory tests and clinical studies performed over an 8 week period on 20 female subjects ranging from 18 to 55 years of age with oily, normal, and dry skin types. SeneDerm™ by SeneGence™ Evening Moisturizer was used in these tests. Remarkable, areas tested showed significant improvement on all subjects. The following documentation reflects the astounding results from these independent laboratory tests.


CELLULAR REMOVAL - 23.3%
Product treatment was shown to be highly effective in increasing cell renewal with an average increased renewal rate of 23.3%. Additionally, the statistical analysis has revealed that the difference seen between the treatment and the control groups are significant at a 95% confidence limit level.

 

MOISTURIZATION AND HYDRATION - 54.2%

Moisture content was assessed via impedance measurements on the cheek area of subjects with moderately dry skin conditions. As early as two weeks of treatment, a significant increase of 20.4% was observed. Increased moisturization and hydration continued throughout the treatment period with improvements of 32.6% 4 weeks and 54.2% at 8 weeks.

FINE LINES AND WRINKLES - 55.7%

Changes in skin texture were assessed by taking Siflo Replicas of the canthus area and analyzing the replicas with a computer image analysis system. As the results indicated, a significant reduction of 23.2% was observed after two weeks of product treatment. As the treatment continued, greater reductions of 38.8% and 55.7% were observed at week 4 and 8 post treatment respectively.

FIRMNESS AND ELASTICITY - 51.9% - Indentometry

Indentometry method measures firmness at deeper layers in the skin (including the full epidermis and dermis). A force is applied perpendicularly to the test area (the cheek of the 20 subjects) and the depth of the indentation is measured in millimeters. As the elastin network becomes more developed, the ability of it to resist elasticity increases and the depth of indentation decreases. After eight weeks usage, approximately 52% reduction in the indentation depth was noted. Test results showed a 51.9% increase in the firmness of the skin. 

LUMINOSITY - 48.7%

Luminosity consists of transparency and color factors which are commonly known as skin tone and degree of redness. Determination of skin luminosity is particularly useful in determining the efficacy of "skin conditioners? and cosmetics. Luminosity studies have been utilized to measure the degree of intracellular metabolism, water content, and oxygen levels. Eight weeks of treatment with SeneDerm™ Evening Moisturizer resulted in 48.7% improvement in skin luminosity.

CLINICAL CONCLUSIONS

The laboratory testing in this study provided results showing that the SeneDerm™ product used in these tests was highly effective in improving skin moisturization and hydration, skin firmness, reducing lines and wrinkles, and increasing cellular renewal. Ultrasound analysis also revealed an increase in skin thickness as well as tissue density with product treatment which led to the improvement in skin firmness. Eight weeks of product treatment also significantly reduced skin pigmentation and consequently improved skin clarity and luminosity. 

"Our labs had performed preliminary tests on the SeneDerm™ products and had documented amazing results, but when we received the results from an independent lab with the clinical data from the scientific studies that they conducted, it was astounding! The percentages of improvement went beyond anything we had imagined. These products are truly revolutionary!"
                                                ----- Yoram Fishman, creator of SeneDerm™ by SeneGence™


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